von Willebrand’s Disease Type 1 DNA Test

How do I Know if my Dog Carries the Mutation for vWD1?

There are three classifications of vWD that are based on the concentration and nature of plasma von Willebrand Factor. Type I von Willebrand’s is characterized by abnormally-low production of protein found in the vWF blood, which is a key factor in the process of clotting a damaged blood vessel. This type of vWF is usually milder and more variable in form than the other types.

vWD is inherited as an autosomal recessive disorder. Therefore, dogs that carry one (1) copy of the vWD mutation may exhibit a reduction in the amount of plasma vWF, but are not likely to be symptomatic.

Our vWD1 DNA test gives breeders an accurate, convenient, and affordable tool to help them avoid producing affected offspring and significantly reduce the gene frequency in future generations.

DNA results are emailed within 5 business days, once all samples are received at the laboratory.

Not sure if you need this test? Check the list below or contact us for a free consultation.

Testing for the vWD1 Mutation is Available for these Breeds
Bernese Mountain Dog, Coton de Tulear, Doberman Pinscher, Drentsche Patrijschond, German Pinscher, Goldendoodle, Kerry Blue Terrier, Labradoodle, Manchester Terrier, Papillion, Pembroke Welsh Corgi, Poodle, Stabyhoun.

Your vWD1 DNA-test kit includes:

• Sterile DNA-collection swabs
• Complete instructions

Understanding Results

There are 3 possible genotypes reported for Hyperuricosuria:  

• CLEAR: those having 2 copies of the normal allele and appear to be normal
• CARRIER: those having 1 copy of the normal allele and 1 copy of the mutation but appear to be normal
• AFFECTED: those having 2 copies of the mutation and are at risk of suffering a severe bleeding incident

Results are based upon the specific von Willebrand’s Type I mutation (c.7437G>A). Clear results for vWD I only pertain to the specific mutation tested. It will not detect if a dog has any other form of bleeding disorder.